CYSLTR2

Across TCGA cell cohorts, CYSLTR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 327 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYSLTR2-associated GO terms across cancer lineages are Regulation of autophagosome assembly, Protein polyubiquitination, and Sodium ion transmembrane transport. Each is linked with CYSLTR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYSLTR2-to-partner and partner-to-CYSLTR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome assembly grouped by CYSLTR2-low versus CYSLTR2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYSLTR2→partner) and Y-score (partner→CYSLTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of autophagosome assembly →	+0.036	+0.116	<.001	.003	3	3
CNS	Protein polyubiquitination →	+0.026	+0.122	<.001	.002	3	3
CNS	Sodium ion transmembrane transport →	-0.041	-0.161	<.001	.004	3	3
CNS	Renal tubule morphogenesis →	-0.031	-0.128	.001	.001	3	3
CNS	Potassium ion transmembrane transport →	-0.036	-0.098	<.001	.005	3	3
LIVER	MHC class I protein complex assembly →	+0.099	+0.018	<.001	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 327 associations by consensus.

Regulation of autophagosome assembly by CYSLTR2 expression — CNS

Explore this box plot interactively →