CYREN

Across TCGA patient cohorts, CYREN protein abundance is significantly associated with the RNA expression of many other genes, with 7,626 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYREN-associated genes across cancer lineages are OR52H1, MORN1, and TSFM. Each is linked with CYREN in more than 1 cancer types. Because this analysis shows association rather than direction, both CYREN-to-partner and partner-to-CYREN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYREN versus OR52H1 in UCEC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYREN→partner) and Y-score (partner→CYREN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR52H1 →	-1.208	-0.350	<.001	<.001	3	2
GBM	MORN1 →	-0.642	-0.522	.002	.005	3	2
PDAC	TSFM →	-0.435	-1.689	<.001	<.001	3	2
LSCC	AP3B1 →	-0.305	-0.427	.005	.002	3	2
LSCC	DCTN4 →	-0.458	-0.393	.001	.004	3	2
GBM	AVIL →	-1.061	-0.406	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,626 associations by consensus.

CYREN vs OR52H1 — UCEC

Explore this scatter interactively →