CYP7B1

Across TCGA patient cohorts, CYP7B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,346 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP7B1-associated proteins across cancer lineages are DAB2, TBC1D2B, and PRKG1. Each is linked with CYP7B1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYP7B1-to-partner and partner-to-CYP7B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP7B1 versus DAB2 in GBM, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP7B1→partner) and Y-score (partner→CYP7B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DAB2 →	+0.499	+0.603	<.001	.002	3	8
OV	TBC1D2B →	+0.319	+0.923	<.001	<.001	3	8
UCEC	PRKG1 →	+0.689	+0.884	<.001	<.001	3	8
UCEC	SEPTIN11 →	+0.440	+0.919	<.001	<.001	3	7
BRCA	SEPTIN7 →	+0.219	+0.712	.001	.006	3	7
COAD	SGCD →	+0.689	+0.858	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,346 associations by consensus.

CYP7B1 vs DAB2 — GBM

Explore this scatter interactively →