CYP7B1

Across TCGA patient cohorts, CYP7B1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,884 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP7B1-associated genes across cancer lineages are PTGFR, CSF2RB, and CD53. Each is linked with CYP7B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP7B1-to-partner and partner-to-CYP7B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP7B1 versus PTGFR in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP7B1→partner) and Y-score (partner→CYP7B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTGFR →	+0.702	+0.689	<.001	<.001	3	6
OV	CSF2RB →	+0.900	+0.557	<.001	<.001	3	6
OV	CD53 →	+1.025	+0.678	<.001	<.001	3	6
CCRCC	CCL18 →	+1.577	+0.258	<.001	<.001	3	6
LUAD	LRRK2-DT →	+1.062	+0.383	.003	<.001	3	5
OV	MEDAG →	+1.729	+0.808	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,884 associations by consensus.

CYP7B1 vs PTGFR — OV

Explore this scatter interactively →