CYP51A1P1

Across TCGA patient cohorts, CYP51A1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP51A1P1-associated GO terms across cancer lineages are Cellular response to ionizing radiation, Vesicle tethering involved in exocytosis, and Mitotic sister chromatid cohesion. Each is linked with CYP51A1P1 in more than 24 cancer types. Because this analysis shows association rather than direction, both CYP51A1P1-to-partner and partner-to-CYP51A1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to ionizing radiation grouped by CYP51A1P1-low versus CYP51A1P1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP51A1P1→partner) and Y-score (partner→CYP51A1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Cellular response to ionizing radiation →	+0.067	+0.108	.002	.001	3	24
STAD	Vesicle tethering involved in exocytosis →	+0.059	+0.262	<.001	<.001	3	23
STAD	Mitotic sister chromatid cohesion →	+0.060	+0.187	<.001	<.001	3	23
STAD	RNA 3'-end processing →	+0.067	+0.239	<.001	<.001	2	24
THYM	Positive regulation of translation in response to stress →	+0.081	+0.079	<.001	<.001	3	23
THYM	Regulation of translational initiation in response to stress →	+0.059	+0.059	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,784 associations by consensus.

Cellular response to ionizing radiation by CYP51A1P1 expression — DLBC

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