Across TCGA patient cohorts, CYP4X1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,427 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYP4X1-associated proteins across cancer lineages are TBL3, WFDC2, and DDAH1. Each is linked with CYP4X1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP4X1-to-partner and partner-to-CYP4X1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4X1→partner) and Y-score (partner→CYP4X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBL3 →	-0.247	-2.261	<.001	<.001	3	6
HNSC	WFDC2 →	+1.178	+1.314	<.001	.001	3	6
BRCA	DDAH1 →	+0.563	+2.064	<.001	<.001	3	6
BRCA	RPS2 →	-0.271	-2.706	<.001	<.001	3	6
BRCA	CYP4X1_S268 →	+1.839	+3.495	<.001	<.001	3	6
GBM	TPPP →	+0.914	+0.691	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,427 associations by consensus.

Exploration

CYP4X1 survival (RNA) · tumor vs normal (RNA) · all CYP4X1 data types