CYP4V2

Across TCGA patient cohorts, CYP4V2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,656 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP4V2-associated genes across cancer lineages are FUCA1, SNHG16, and KLKB1. Each is linked with CYP4V2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP4V2-to-partner and partner-to-CYP4V2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4V2 versus FUCA1 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4V2→partner) and Y-score (partner→CYP4V2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FUCA1 →	+0.577	+0.315	<.001	<.001	3	4
LUAD	SNHG16 →	-0.571	-0.472	.003	.001	3	3
CCRCC	KLKB1 →	+0.919	+0.353	<.001	<.001	3	3
LUAD	EEF2 →	-0.562	-0.481	<.001	<.001	3	3
LUAD	IMPDH2 →	-0.509	-0.457	<.001	.001	3	3
LUAD	RPL23A →	-0.494	-0.581	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,656 associations by consensus.

CYP4V2 vs FUCA1 — LSCC

Explore this scatter interactively →