CYP4V2

Across TCGA cell cohorts, CYP4V2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,426 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CYP4V2-associated GO terms across cancer lineages are Fatty acid omega-oxidation, Phospholipid biosynthetic process, and Endoplasmic reticulum to cytosol transport. Each is linked with CYP4V2 in more than 11 cancer types. Because this analysis shows association rather than direction, both CYP4V2-to-partner and partner-to-CYP4V2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid omega-oxidation grouped by CYP4V2-low versus CYP4V2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4V2→partner) and Y-score (partner→CYP4V2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Fatty acid omega-oxidation →	-0.291	-1.565	<.001	<.001	3	12
BLOOD_Myeloma	Phospholipid biosynthetic process →	+0.030	+2.126	<.001	<.001	3	10
OESOPHAGUS	Endoplasmic reticulum to cytosol transport →	+0.143	+1.289	.002	<.001	3	10
OESOPHAGUS	Retrograde protein transport, ER to cytosol →	+0.143	+1.289	.002	<.001	3	10
LUNG_SCLC	Fatty acid catabolic process →	+0.063	+1.373	.007	.005	2	10
LARGE_INTESTINE	Sperm motility →	-0.107	-1.274	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,426 associations by consensus.

Fatty acid omega-oxidation by CYP4V2 expression — BONE

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