CYP4F35P

Across TCGA patient cohorts, CYP4F35P mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F35P-associated genes across cancer lineages are eEF2, Ku80, and NDRG1_pT346. Each is linked with CYP4F35P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F35P-to-partner and partner-to-CYP4F35P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CYP4F35P-low versus CYP4F35P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F35P→partner) and Y-score (partner→CYP4F35P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.563	+3.169	.004	.020	3	1
UCEC	Ku80 →	+0.340	+3.183	.008	.010	3	1
UCEC	NDRG1_pT346 →	-0.595	-3.169	.027	.019	3	1
UCEC	PCNA →	+0.248	+3.000	.036	.036	3	1
UCEC	STAT3_pY705 →	-0.566	-3.159	<.001	.019	3	1
UCEC	Tuberin →	+0.428	+3.009	.003	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

eEF2 by CYP4F35P expression — UCEC

Explore this box plot interactively →