CYP4F34P

Across TCGA pan-cancer cohorts, CYP4F34P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CYP4F34P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CYP4F34P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYP4F34P expression acts as an unfavorable survival marker, although some lineages such as MESO and LGG show a favorable association.

KIRP, COAD, and KIRC are the cancer types where CYP4F34P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.377	0.763	<.001	141	view →
COAD	OS	Tertile	III,IV	0.346	0.729	.002	84	view →
KIRC	DFS	Tertile	III,IV	0.303	0.515	.002	58	view →
STAD	DFS	Tertile	All	0.289	0.430	.008	54	view →
MESO	OS	Tertile	All	0.559	0.334	.010	25	view →
PRAD	OS	Quartile	All	0.967	0.997	.007	24	view →
LGG	OS	Tertile	All	0.867	0.780	.008	20	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
ESCA	OS	Tertile	IV	0.743	0.339	.017	18	view →
CESC	OS	Tertile	IV	0.664	0.195	.031	18	view →
LUAD	DFS	Tertile	II,III,IV	0.604	0.773	.022	16	view →
LIHC	OS	Tertile	All	0.561	0.720	.018	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CYP4F34P–KIRP (OS)

Open the KIRP breakdown →