Across TCGA pan-cancer cohorts, CYP4F26P RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CYP4F26P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CYP4F26P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYP4F26P expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

KIRC, UCS, and MESO are the cancer types where CYP4F26P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.496	0.689	<.001	114	view →
UCS	DFS	Quartile	II,III,IV	0.627	0.109	.002	58	view →
MESO	OS	Tertile	IV	0.129	0.679	<.001	55	view →
ACC	DFS	Tertile	IV	0.172	0.499	.011	47	view →
BLCA	OS	Median	IV	0.401	0.180	.002	42	view →
LUAD	DFS	Tertile	All	0.576	0.711	.003	40	view →
UCEC	DFS	Tertile	All	0.557	0.687	.023	24	view →
PAAD	OS	Tertile	II,III,IV	0.483	0.737	.007	23	view →
UVM	DFS	Tertile	II,III,IV	0.396	0.653	.032	22	view →
COAD	DFS	Median	All	0.387	0.617	.005	17	view →
LUSC	OS	Quartile	II,III,IV	0.815	0.668	.013	15	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration

Same gene, other analysis: CYP4F26P tumor-vs-normal RNA expression · all CYP4F26P data types