CYP4F23P

Across TCGA pan-cancer cohorts, CYP4F23P RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CYP4F23P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CYP4F23P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CYP4F23P is over-expressed in tumor.

COAD, KIRP, and LUAD are the cancer types where CYP4F23P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYP4F23P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.846	<.001	11	view →
KIRP	Female	All	+0.939	<.001	10	view →
LUAD	All	All	+0.313	<.001	7	view →
BRCA	All	II,III,IV	+0.909	<.001	6	view →
LUSC	Male	All	+0.194	<.001	5	view →
THCA	Female	All	+0.035	.006	3	view →
KIRC	Male	All	+0.034	.009	3	view →
CHOL	All	All	+2.278	<.001	2	view →
BLCA	All	All	+1.077	.039	2	view →
LIHC	All	All	+0.204	.048	1	view →
STAD	Male	All	+0.173	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CYP4F23P–COAD

Open the COAD breakdown →