CYP4F22

Across TCGA patient cohorts, CYP4F22 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,690 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP4F22-associated proteins across cancer lineages are SORBS1, SRRM2_S1582, and MARCKSL1. Each is linked with CYP4F22 in more than 2 cancer types. Because this analysis shows association rather than direction, both CYP4F22-to-partner and partner-to-CYP4F22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4F22 versus SORBS1 in BRCA, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F22→partner) and Y-score (partner→CYP4F22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SORBS1 →	+0.647	+1.365	<.001	<.001	3	3
OV	SRRM2_S1582 →	-1.071	-0.175	.002	.003	3	3
GBM	MARCKSL1 →	-0.586	-0.096	<.001	.006	3	3
LUAD	RNPEP →	+0.264	+0.172	<.001	<.001	3	3
BRCA	EVL →	+0.416	+1.024	<.001	<.001	3	3
HNSC	GLTP →	+0.586	+1.394	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,690 associations by consensus.

CYP4F22 vs SORBS1 — BRCA

Explore this scatter interactively →