CYP4F22

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYP4F22 protein abundance is significantly associated with the RNA expression of many other genes, with 4,029 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CYP4F22-associated genes across cancer lineages are KMO, CARHSP1, and KRT9. Each is linked with CYP4F22 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F22-to-partner and partner-to-CYP4F22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4F22 versus KMO in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F22→partner) and Y-score (partner→CYP4F22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAKMO →-1.213-0.836<.001.00532
HNSCCARHSP1 →+0.814+1.131<.001<.00132
HNSCKRT9 →+0.749+0.800<.001<.00132
LSCCCCDC85C →+1.370+1.799<.001.00132
HNSCTRDC →-0.970-0.773<.001<.00132
LSCCRPSAP24 →+0.556+1.733.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,029 associations by consensus.

CYP4F22 vs KMO — BRCA

Per-sample scatter of CYP4F22 vs KMO in BRCA (Pearson r = -0.38).

Explore this scatter interactively →

Exploration