CYP4F22

Across TCGA cell cohorts, CYP4F22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,021 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYP4F22-associated GO terms across cancer lineages are Aldosterone biosynthetic process, Response to amino acid starvation, and Negative regulation of testosterone biosynthetic process. Each is linked with CYP4F22 in more than 6 cancer types. Because this analysis shows association rather than direction, both CYP4F22-to-partner and partner-to-CYP4F22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldosterone biosynthetic process grouped by CYP4F22-low versus CYP4F22-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F22→partner) and Y-score (partner→CYP4F22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Aldosterone biosynthetic process →	+1.467	+3.963	<.001	<.001	3	7
SOFT_TISSUE	Response to amino acid starvation →	+0.055	+0.536	.001	.002	3	5
BONE	Negative regulation of testosterone biosynthetic process →	-0.223	-3.519	<.001	<.001	3	5
SOFT_TISSUE	Negative regulation of interferon-alpha production →	+0.549	+0.512	<.001	.001	3	5
BONE	Copper ion export →	-0.194	-5.354	<.001	<.001	3	5
BONE	Positive regulation of sodium ion transport →	-0.164	-3.342	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,021 associations by consensus.

Aldosterone biosynthetic process by CYP4F22 expression — BONE

Explore this box plot interactively →