CYP4F22

Across TCGA cell cohorts, CYP4F22 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP4F22-associated genes across cancer lineages are T0901317, ETP-45835, and Palbociclib. Each is linked with CYP4F22 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F22-to-partner and partner-to-CYP4F22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T0901317 grouped by CYP4F22-low versus CYP4F22-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F22→partner) and Y-score (partner→CYP4F22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	T0901317 →	+0.355	+2.722	.009	.040	2	2
LARGE_INTESTINE	ETP-45835 →	+0.241	+2.652	.046	.045	3	1
LARGE_INTESTINE	Palbociclib →	+0.547	+2.646	.025	.047	2	1
LARGE_INTESTINE	CP466722 →	+0.497	+2.652	.011	.045	2	1
LARGE_INTESTINE	IWP-2 →	+0.357	+2.893	.006	.034	2	1
LARGE_INTESTINE	Quizartinib →	+0.417	+2.652	.008	.045	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

T0901317 by CYP4F22 expression — LARGE_INTESTINE

Explore this box plot interactively →