Across TCGA cell cohorts, CYP4F2 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP4F2-associated genes across cancer lineages are ACTL7A, PRL, and RETNLB. Each is linked with CYP4F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F2-to-partner and partner-to-CYP4F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F2→partner) and Y-score (partner→CYP4F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ACTL7A →	+0.041	+4.044	<.001	.005	3	1
LUNG_NSCLC_LUSC	PRL →	+0.024	+4.584	<.001	.001	3	1
LUNG_NSCLC_LUAD	RETNLB →	+0.122	+3.215	.008	.007	3	1
LUNG_NSCLC_LUAD	UMOD →	+0.003	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	UTF1 →	+0.303	+3.786	.002	.001	3	1
LUNG_NSCLC_LUAD	DAOA →	+0.011	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

CYP4F2 survival (RNA) · tumor vs normal (RNA) · all CYP4F2 data types