CYP4F11

Across TCGA patient cohorts, CYP4F11 protein abundance is significantly associated with the RNA expression of many other genes, with 10,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP4F11-associated genes across cancer lineages are CYP4F12, CYP4F3, and NMRAL2P. Each is linked with CYP4F11 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP4F11-to-partner and partner-to-CYP4F11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4F11 versus CYP4F12 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F11→partner) and Y-score (partner→CYP4F11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYP4F12 →	+1.317	+1.112	<.001	<.001	3	6
LSCC	CYP4F3 →	+3.777	+2.036	<.001	<.001	3	6
LSCC	NMRAL2P →	+4.374	+1.995	<.001	<.001	3	5
LSCC	NQO1 →	+2.363	+2.028	<.001	<.001	3	5
LSCC	AKR1C3 →	+3.198	+1.710	<.001	<.001	3	5
LSCC	AKR1B10 →	+3.929	+2.044	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,006 associations by consensus.

CYP4F11 vs CYP4F12 — UCEC

Explore this scatter interactively →