CYP4F11

Across TCGA cell cohorts, CYP4F11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,901 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CYP4F11-associated GO terms across cancer lineages are Menaquinone catabolic process, Terpenoid catabolic process, and Leukotriene B4 catabolic process. Each is linked with CYP4F11 in more than 17 cancer types. Because this analysis shows association rather than direction, both CYP4F11-to-partner and partner-to-CYP4F11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Menaquinone catabolic process grouped by CYP4F11-low versus CYP4F11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F11→partner) and Y-score (partner→CYP4F11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Menaquinone catabolic process →	+2.126	+4.528	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Terpenoid catabolic process →	+1.476	+4.384	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Leukotriene B4 catabolic process →	+1.921	+4.802	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Response to L-phenylalanine derivative →	+0.123	+2.860	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Isoprenoid catabolic process →	+1.497	+4.384	<.001	<.001	3	12
URINARY_TRACT	Prostaglandin metabolic process →	+0.219	+2.466	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

Menaquinone catabolic process by CYP4F11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →