CYP4A27P

Across TCGA pan-cancer cohorts, CYP4A27P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated CYP4A27P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CYP4A27P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYP4A27P expression acts as an unfavorable survival marker, although some lineages such as LUAD and LUSC show a favorable association.

ACC, STAD, and LIHC are the cancer types where CYP4A27P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
STAD	OS	Tertile	II,III,IV	0.439	0.730	.009	36	view →
LIHC	OS	Tertile	III,IV	0.051	0.738	<.001	36	view →
LAML	DFS	Tertile	All	0.111	0.590	<.001	36	view →
PCPG	OS	Tertile	All	0.032	0.948	<.001	27	view →
LUAD	OS	Tertile	All	0.817	0.667	.020	24	view →
KIRC	DFS	Tertile	IV	0.176	0.638	.025	18	view →
THCA	DFS	Tertile	IV	0.126	0.805	.002	18	view →
OV	OS	Tertile	IV	0.204	0.409	.024	6	view →
LUSC	DFS	Tertile	II,III,IV	1.000	0.575	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

CYP4A27P–ACC (OS)

Open the ACC breakdown →