CYP4A22

Across TCGA patient cohorts, CYP4A22 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,155 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP4A22-associated proteins across cancer lineages are MYO6, RBM42, and RCOR1_S127. Each is linked with CYP4A22 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP4A22-to-partner and partner-to-CYP4A22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4A22 versus MYO6 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4A22→partner) and Y-score (partner→CYP4A22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYO6 →	+0.444	+0.545	<.001	<.001	3	4
GBM	RBM42 →	-0.213	-0.251	.002	.002	3	3
BRCA	RCOR1_S127 →	-0.512	-0.535	.001	.001	3	3
BRCA	SAP30BP →	-0.239	-0.530	<.001	.001	3	3
LSCC	KIAA1522_T162 →	+0.640	+0.545	<.001	<.001	3	3
CCRCC	ACAD11 →	+0.523	+0.603	.009	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,155 associations by consensus.

CYP4A22 vs MYO6 — LSCC

Explore this scatter interactively →