CYP4A22

Across TCGA cell cohorts, CYP4A22 RNA expression is significantly associated with the go_rna of many other GO terms, with 982 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYP4A22-associated GO terms across cancer lineages are Lauric acid metabolic process, Cilium movement, and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Each is linked with CYP4A22 in more than 12 cancer types. Because this analysis shows association rather than direction, both CYP4A22-to-partner and partner-to-CYP4A22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lauric acid metabolic process grouped by CYP4A22-low versus CYP4A22-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4A22→partner) and Y-score (partner→CYP4A22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lauric acid metabolic process →	+0.786	+0.110	<.001	.007	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement →	-0.093	-0.024	.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	-0.101	-0.021	.009	.003	2	6
STOMACH	Negative regulation of translational initiation →	+0.088	+0.015	.006	.005	2	6
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.074	-0.020	.004	.002	3	5
KIDNEY	Flagellated sperm motility →	-0.083	-0.033	.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 982 associations by consensus.

Lauric acid metabolic process by CYP4A22 expression — BREAST

Explore this box plot interactively →