CYP3A7

Across TCGA patient cohorts, CYP3A7 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,019 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYP3A7-associated proteins across cancer lineages are CTSC, NRBF2, and PTPRC_S994. Each is linked with CYP3A7 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP3A7-to-partner and partner-to-CYP3A7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP3A7 versus CTSC in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP3A7→partner) and Y-score (partner→CYP3A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSC →	-0.503	-0.257	<.001	<.001	3	4
GBM	NRBF2 →	-0.339	-0.323	<.001	<.001	3	4
GBM	PTPRC_S994 →	-0.938	-0.293	<.001	<.001	3	4
OV	HBP1_S135 →	+0.642	+0.094	<.001	.009	3	3
GBM	G6PD →	-0.340	-0.300	<.001	<.001	3	3
COAD	HDLBP_S944 →	-0.822	-0.102	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,019 associations by consensus.

CYP3A7 vs CTSC — GBM

Explore this scatter interactively →