CYP3A54P

Across TCGA pan-cancer cohorts, CYP3A54P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated CYP3A54P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher CYP3A54P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYP3A54P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

ESCA, LIHC, and CESC are the cancer types where CYP3A54P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LIHC	OS	Tertile	All	0.025	0.777	<.001	36	view →
CESC	DFS	Tertile	All	0.233	0.740	.023	18	view →
SKCM	DFS	Tertile	All	1.000	0.623	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CYP3A54P–ESCA (OS)

Open the ESCA breakdown →