CYP3A43

Across TCGA patient cohorts, CYP3A43 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,204 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CYP3A43-associated proteins across cancer lineages are TCIRG1, RPL14, and PDS5B. Each is linked with CYP3A43 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP3A43-to-partner and partner-to-CYP3A43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP3A43 versus TCIRG1 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP3A43→partner) and Y-score (partner→CYP3A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TCIRG1 →	-0.417	-0.536	<.001	<.001	3	4
GBM	RPL14 →	-0.344	-0.475	.003	<.001	3	4
COAD	PDS5B →	+0.282	+0.105	<.001	.002	3	4
HNSC	ZNF219_S114 →	+0.690	+0.318	.001	<.001	3	3
HNSC	ZNF768 →	+0.807	+0.346	<.001	<.001	3	3
CCRCC	PSMC5 →	-0.146	-0.377	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,204 associations by consensus.

CYP3A43 vs TCIRG1 — GBM

Explore this scatter interactively →