CYP3A43

Across TCGA patient cohorts, CYP3A43 protein abundance is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP3A43-associated genes across cancer lineages are ARFRP1, TMEM33, and BTN3A3. Each is linked with CYP3A43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP3A43-to-partner and partner-to-CYP3A43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP3A43 versus ARFRP1 in BRCA, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP3A43→partner) and Y-score (partner→CYP3A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFRP1 →	+0.896	+3.043	.008	.001	3	1
BRCA	TMEM33 →	+0.696	+2.615	.002	.001	3	1
BRCA	BTN3A3 →	-0.889	-3.403	.005	.001	3	1
BRCA	HES1 →	+1.256	+2.615	.001	.001	3	1
BRCA	CTBS →	+0.588	+2.615	.005	.001	3	1
BRCA	SLURP1 →	+0.628	+2.615	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

CYP3A43 vs ARFRP1 — BRCA

Explore this scatter interactively →