Across TCGA patient cohorts, CYP2R1 protein abundance is significantly associated with the protein abundance of many other proteins, with 499 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CYP2R1-associated proteins across cancer lineages are ANGPT2, ANK2_S3823, and ANKRD10_S353. Each is linked with CYP2R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2R1-to-partner and partner-to-CYP2R1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2R1→partner) and Y-score (partner→CYP2R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ANGPT2 →	-1.236	-0.666	.009	.005	2	1
LUAD	ANK2_S3823 →	-0.403	-0.633	.004	.004	2	1
LUAD	ANKRD10_S353 →	+0.589	+0.696	.002	.003	2	1
LUAD	ABLIM1_S706 →	+0.583	+0.606	.007	.005	2	1
LUAD	ANO8_S641 →	+1.030	+0.686	.007	.004	2	1
LUAD	ARHGEF17_S138 →	+0.688	+0.746	.005	<.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 499 associations by consensus.

Exploration

CYP2R1 survival (RNA) · tumor vs normal (RNA) · all CYP2R1 data types