CYP2R1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CYP2R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,224 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CYP2R1-associated GO terms across cancer lineages are Calcitriol biosynthetic process from calciol, Vitamin D biosynthetic process, and Vitamin D3 metabolic process. Each is linked with CYP2R1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CYP2R1-to-partner and partner-to-CYP2R1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2R1→partner) and Y-score (partner→CYP2R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHCalcitriol biosynthetic process from calciol →+1.308+1.801<.001.001312
STOMACHVitamin D biosynthetic process →+1.308+1.801<.001.001312
STOMACHVitamin D3 metabolic process →+1.308+1.801<.001.001312
STOMACHVesicle coating →+0.065+0.975<.001.00839
UPPER_AERODIGESTIVE_TRACTRegulation of myoblast fusion →+0.087+1.292.007.00139
LUNG_NSCLC_LUSCFat-soluble vitamin biosynthetic process →+0.991+0.842.005.00929
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,224 associations by consensus.

Exploration