CYP2J2

Across TCGA cell cohorts, CYP2J2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,995 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYP2J2-associated GO terms across cancer lineages are Action potential propagation, Lipoxygenase pathway, and Vacuolar transport. Each is linked with CYP2J2 in more than 10 cancer types. Because this analysis shows association rather than direction, both CYP2J2-to-partner and partner-to-CYP2J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Action potential propagation grouped by CYP2J2-low versus CYP2J2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2J2→partner) and Y-score (partner→CYP2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Action potential propagation →	-0.697	-0.906	.002	.002	3	11
LUNG_NSCLC_LUAD	Lipoxygenase pathway →	-0.152	-0.784	.001	<.001	3	9
STOMACH	Vacuolar transport →	+0.094	+1.551	.001	<.001	3	9
BONE	Negative regulation of T cell mediated cytotoxicity →	+2.199	+2.014	<.001	<.001	3	8
LUNG_SCLC	Secretion by tissue →	+0.262	+1.216	.001	.003	3	8
URINARY_TRACT	Surfactant homeostasis →	+0.257	+2.783	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,995 associations by consensus.

Action potential propagation by CYP2J2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →