CYP2J2

Across TCGA cell cohorts, CYP2J2 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYP2J2-associated genes across cancer lineages are RHOXF1, KRT37, and KLRF1. Each is linked with CYP2J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2J2-to-partner and partner-to-CYP2J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RHOXF1 grouped by CYP2J2-low versus CYP2J2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2J2→partner) and Y-score (partner→CYP2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RHOXF1 →	+0.093	+3.936	<.001	.002	3	1
SOFT_TISSUE	KRT37 →	+0.068	+3.459	.008	.003	3	1
SOFT_TISSUE	KLRF1 →	+0.120	+3.491	.002	.008	3	1
SOFT_TISSUE	ATP6V1G3 →	+0.716	+4.186	<.001	.001	3	1
SOFT_TISSUE	CAPSL →	+0.544	+3.807	<.001	.003	3	1
SOFT_TISSUE	RTP3 →	+0.151	+3.936	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RHOXF1 by CYP2J2 expression — SOFT_TISSUE

Explore this box plot interactively →