Across TCGA patient cohorts, CYP2F1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP2F1-associated genes across cancer lineages are mTOR_pS2448, ASNS, and Bim. Each is linked with CYP2F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2F1-to-partner and partner-to-CYP2F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2F1→partner) and Y-score (partner→CYP2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.113	-1.980	.028	.030	3	2
UCEC	ASNS →	+0.357	+2.700	.004	.005	3	2
UCEC	Bim →	-0.204	-1.736	.025	.007	3	2
UCEC	Cyclin-B1 →	+0.417	+1.440	.032	.024	3	2
SKCM	ACC_pS79 →	+0.376	+3.169	.017	.019	3	2
UCEC	EGFR_pY1068 →	-0.214	-2.070	.014	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

CYP2F1 survival (RNA) · tumor vs normal (RNA) · all CYP2F1 data types