Across TCGA cell cohorts, CYP2F1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,678 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYP2F1-associated GO terms across cancer lineages are Negative regulation of autophagy, Negative regulation of protein-containing complex assembly, and Regulation of protein localization to nucleus. Each is linked with CYP2F1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYP2F1-to-partner and partner-to-CYP2F1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2F1→partner) and Y-score (partner→CYP2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of autophagy →	+0.065	+0.171	<.001	<.001	3	9
STOMACH	Negative regulation of protein-containing complex assembly →	+0.080	+0.229	<.001	.001	3	8
PANCREAS	Regulation of protein localization to nucleus →	+0.067	+0.127	<.001	.002	2	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to nucleus →	+0.097	+0.151	<.001	.002	3	7
BONE	Negative regulation of RNA splicing →	+0.096	+0.279	<.001	<.001	3	7
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.101	+0.286	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,678 associations by consensus.

Exploration

CYP2F1 survival (RNA) · tumor vs normal (RNA) · all CYP2F1 data types