CYP2E1

Across TCGA cell cohorts, CYP2E1 RNA expression is significantly associated with the RNA expression of many other genes, with 5,299 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYP2E1-associated genes across cancer lineages are LHPP, DNAH1, and GOLGA6L4. Each is linked with CYP2E1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CYP2E1-to-partner and partner-to-CYP2E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP2E1 versus LHPP in BLOOD_Lymphoma, with a Pearson correlation of 0.40.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2E1→partner) and Y-score (partner→CYP2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LHPP →	+1.068	+0.460	<.001	.001	3	6
KIDNEY	DNAH1 →	+1.202	+1.037	.004	<.001	1	7
LARGE_INTESTINE	GOLGA6L4 →	+0.855	+0.965	<.001	<.001	3	5
KIDNEY	ATP2A1 →	+1.225	+0.702	<.001	<.001	3	5
BLOOD_Myeloma	KDM6B →	+1.416	+1.056	<.001	.001	2	5
URINARY_TRACT	TRIM73 →	+1.489	+1.487	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,299 associations by consensus.

CYP2E1 vs LHPP — BLOOD_Lymphoma

Explore this scatter interactively →