Across TCGA patient cohorts, CYP2D8P RNA expression is significantly associated with the protein abundance of many other proteins, with 9,594 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYP2D8P-associated proteins across cancer lineages are XRCC5, XRCC6, and MORC2. Each is linked with CYP2D8P in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP2D8P-to-partner and partner-to-CYP2D8P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2D8P→partner) and Y-score (partner→CYP2D8P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	XRCC5 →	+0.304	+0.536	<.001	<.001	3	4
GBM	XRCC6 →	+0.226	+0.353	<.001	<.001	3	4
LSCC	MORC2 →	+0.322	+0.433	.005	.002	3	4
PDAC	NRF1 →	+0.367	+0.266	.003	.003	2	5
HNSC	TCF20 →	+0.297	+0.686	<.001	<.001	3	4
BRCA	RAD21 →	+0.187	+0.396	.002	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,594 associations by consensus.

Exploration

CYP2D8P survival (RNA) · tumor vs normal (RNA) · all CYP2D8P data types