CYP2C58P

Across TCGA pan-cancer cohorts, CYP2C58P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CYP2C58P data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CYP2C58P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYP2C58P expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

LUAD, GBM, and COAD are the cancer types where CYP2C58P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	IV	0.104	0.611	.003	54	view →
GBM	OS	Tertile	All	0.033	0.416	<.001	36	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	27	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
CHOL	DFS	Quartile	II,III,IV	0.093	0.412	.013	15	view →
STAD	DFS	Quartile	IV	0.095	0.470	.001	13	view →
CESC	OS	Tertile	All	0.994	0.860	.034	12	view →
READ	DFS	Tertile	All	0.162	0.559	.039	9	view →
SARC	DFS	Tertile	All	0.130	0.632	.045	9	view →
PAAD	OS	Quartile	All	0.206	0.394	.020	3	view →
SKCM	OS	Tertile	All	1.000	0.332	.027	3	view →
LUSC	DFS	Tertile	II,III,IV	0.878	0.699	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CYP2C58P–LUAD (DFS)

Open the LUAD breakdown →