CYP2C18

Across TCGA patient cohorts, CYP2C18 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,970 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP2C18-associated proteins across cancer lineages are TACC2_S2512, CORO2A, and AKR1B10. Each is linked with CYP2C18 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP2C18-to-partner and partner-to-CYP2C18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP2C18 versus TACC2_S2512 in LUAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2C18→partner) and Y-score (partner→CYP2C18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TACC2_S2512 →	+0.726	+0.958	.002	.006	3	5
PDAC	CORO2A →	+0.510	+1.266	<.001	<.001	3	5
LUAD	AKR1B10 →	+1.915	+1.223	.002	.002	3	5
HNSC	PLOD2 →	-0.708	-1.591	<.001	<.001	3	4
LSCC	POF1B →	+0.940	+1.073	<.001	<.001	3	4
COAD	RELCH →	+0.302	+1.179	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,970 associations by consensus.

CYP2C18 vs TACC2_S2512 — LUAD

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