CYP2B7P

Across TCGA patient cohorts, CYP2B7P mutation is significantly associated with the RNA expression of many other genes, with 431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP2B7P-associated genes across cancer lineages are RNA5SP86, DHRS11, and EZH2P1. Each is linked with CYP2B7P in more than 2 cancer types. Because this analysis shows association rather than direction, both CYP2B7P-to-partner and partner-to-CYP2B7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP86 grouped by CYP2B7P-low versus CYP2B7P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2B7P→partner) and Y-score (partner→CYP2B7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP86 →	+0.633	+2.921	<.001	<.001	3	3
SKCM	DHRS11 →	+0.529	+3.207	.009	.009	3	2
UCEC	EZH2P1 →	+0.266	+1.816	.005	.007	3	2
UCEC	TAPBP →	-0.517	-2.300	.002	.006	3	2
UCEC	SNHG21 →	+0.651	+3.732	<.001	<.001	3	2
UCEC	S100A11 →	-0.599	-3.000	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 431 associations by consensus.

RNA5SP86 by CYP2B7P expression — UCEC

Explore this box plot interactively →