Across TCGA patient cohorts, CYP2B6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,942 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CYP2B6-associated GO terms across cancer lineages are Nucleoside bisphosphate metabolic process, Thioester metabolic process, and Lipid oxidation. Each is linked with CYP2B6 in more than 12 cancer types. Because this analysis shows association rather than direction, both CYP2B6-to-partner and partner-to-CYP2B6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2B6→partner) and Y-score (partner→CYP2B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside bisphosphate metabolic process →	+0.041	+1.242	<.001	<.001	2	13
ESCA	Thioester metabolic process →	+0.043	+1.420	<.001	<.001	3	12
ESCA	Lipid oxidation →	+0.045	+1.001	<.001	.001	3	10
ESCA	Fatty-acyl-CoA metabolic process →	+0.060	+1.759	<.001	<.001	3	10
CHOL	Bile acid metabolic process →	+0.065	+3.474	<.001	<.001	3	10
CHOL	Amino acid catabolic process →	+0.055	+3.465	.003	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,942 associations by consensus.

Exploration

CYP2B6 survival (RNA) · tumor vs normal (RNA) · all CYP2B6 data types