Across TCGA cell cohorts, CYP2B6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,475 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP2B6-associated GO terms across cancer lineages are Regulation of cytotoxic T cell degranulation, Negative regulation of cytotoxic T cell degranulation, and Pressure natriuresis. Each is linked with CYP2B6 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP2B6-to-partner and partner-to-CYP2B6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2B6→partner) and Y-score (partner→CYP2B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of cytotoxic T cell degranulation →	+1.392	+1.271	<.001	.009	3	6
URINARY_TRACT	Negative regulation of cytotoxic T cell degranulation →	+1.392	+1.271	<.001	.009	3	6
URINARY_TRACT	Pressure natriuresis →	+1.348	+1.400	<.001	.003	3	5
LARGE_INTESTINE	Serotonin biosynthetic process →	+1.474	+2.292	<.001	<.001	3	5
LARGE_INTESTINE	Cellular response to aldosterone →	+0.182	+1.225	.001	.005	3	5
LARGE_INTESTINE	Negative regulation of T cell mediated cytotoxicity →	+1.301	+2.494	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,475 associations by consensus.

Exploration

CYP2B6 survival (RNA) · tumor vs normal (RNA) · all CYP2B6 data types