CYP2AB1P

Across TCGA pan-cancer cohorts, CYP2AB1P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CYP2AB1P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher CYP2AB1P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYP2AB1P expression acts as an unfavorable survival marker, although some lineages such as COAD and BLCA show a favorable association.

KICH, KIRC, and STAD are the cancer types where CYP2AB1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.041	0.894	<.001	99	view →
KIRC	DFS	Tertile	III,IV	0.295	0.539	<.001	79	view →
STAD	DFS	Quartile	II,III,IV	0.449	0.695	.001	37	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
COAD	DFS	Tertile	All	0.847	0.497	.011	27	view →
BLCA	OS	Quartile	II,III,IV	0.784	0.658	.005	24	view →
ACC	DFS	Tertile	All	0.163	0.534	.004	24	view →
OV	OS	Tertile	IV	0.922	0.704	.028	24	view →
HNSC	DFS	Median	IV	0.709	0.442	.008	21	view →
GBM	DFS	Tertile	All	0.439	0.233	.014	18	view →
READ	OS	Tertile	III,IV	1.000	0.328	.031	18	view →
LUAD	DFS	Tertile	All	0.540	0.692	.031	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CYP2AB1P–KICH (DFS)

Open the KICH breakdown →