CYP2A6

Across TCGA patient cohorts, CYP2A6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,599 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP2A6-associated proteins across cancer lineages are RPL7, SUGT1_S281, and PHC3. Each is linked with CYP2A6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP2A6-to-partner and partner-to-CYP2A6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP2A6 versus RPL7 in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A6→partner) and Y-score (partner→CYP2A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL7 →	-0.439	-2.101	<.001	.002	3	5
HNSC	SUGT1_S281 →	-0.837	-0.821	.006	.003	3	4
BRCA	PHC3 →	+0.518	+2.433	<.001	<.001	3	4
CCRCC	SYS1 →	-0.384	-0.307	<.001	<.001	3	3
BRCA	TNS2 →	+0.455	+1.836	<.001	.006	3	3
BRCA	NUP153 →	-0.264	-1.599	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,599 associations by consensus.

CYP2A6 vs RPL7 — BRCA

Explore this scatter interactively →