Across TCGA patient cohorts, CYP2A13 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP2A13-associated genes across cancer lineages are GAPDH, p38-MAPK_pT180_Y182, and eEF2. Each is linked with CYP2A13 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP2A13-to-partner and partner-to-CYP2A13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A13→partner) and Y-score (partner→CYP2A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.436	+3.169	.024	.018	3	4
UCEC	p38-MAPK_pT180_Y182 →	-0.515	-2.308	.001	.001	3	3
UCEC	eEF2 →	+0.386	+3.321	.002	.009	3	2
UCEC	JNK_pT183_Y185 →	-0.159	-2.584	.008	.010	3	2
UCEC	NF-kB-p65_pS536 →	-0.340	-2.321	.038	.033	3	2
UCEC	PKC-b-II_pS660 →	-0.248	-1.925	.012	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

CYP2A13 survival (RNA) · tumor vs normal (RNA) · all CYP2A13 data types