Across TCGA patient cohorts, CYP27C1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,501 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP27C1-associated proteins across cancer lineages are AHNAK2_S260, ZYX, and SEC23B. Each is linked with CYP27C1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP27C1-to-partner and partner-to-CYP27C1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP27C1→partner) and Y-score (partner→CYP27C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AHNAK2_S260 →	+1.335	+0.877	<.001	<.001	3	6
BRCA	ZYX →	+0.438	+0.728	<.001	<.001	2	6
OV	SEC23B →	-0.335	-0.349	.002	.008	3	5
BRCA	NXN →	+0.597	+0.552	<.001	<.001	3	5
UCEC	ITGA5 →	+0.469	+0.650	<.001	.004	3	5
BRCA	MMP14 →	+0.798	+0.719	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,501 associations by consensus.

Exploration

CYP27C1 survival (RNA) · tumor vs normal (RNA) · all CYP27C1 data types