Across TCGA cell cohorts, CYP27C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,725 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CYP27C1-associated GO terms across cancer lineages are Positive regulation of cell-substrate adhesion, Regulation of hemostasis, and Regulation of blood coagulation. Each is linked with CYP27C1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYP27C1-to-partner and partner-to-CYP27C1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP27C1→partner) and Y-score (partner→CYP27C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of cell-substrate adhesion →	+0.087	+0.929	<.001	<.001	3	8
BREAST	Regulation of hemostasis →	+0.157	+1.093	<.001	.002	3	8
BREAST	Regulation of blood coagulation →	+0.157	+1.093	<.001	.002	3	8
BREAST	Positive regulation of focal adhesion assembly →	+0.158	+0.946	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Ameboidal-type cell migration →	+0.121	+0.912	<.001	<.001	3	7
BONE	Protein localization to basolateral plasma membrane →	+0.159	+1.804	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,725 associations by consensus.

Exploration

CYP27C1 survival (RNA) · tumor vs normal (RNA) · all CYP27C1 data types