CYP19A1

Across TCGA patient cohorts, CYP19A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,926 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYP19A1-associated proteins across cancer lineages are MAP1B, MAP1B_S1427, and XRCC1. Each is linked with CYP19A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP19A1-to-partner and partner-to-CYP19A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP19A1 versus MAP1B in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP19A1→partner) and Y-score (partner→CYP19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MAP1B →	+0.628	+0.294	<.001	<.001	3	4
LSCC	MAP1B_S1427 →	+0.893	+0.632	.005	.002	3	4
GBM	XRCC1 →	-0.366	-0.621	<.001	.001	3	4
GBM	NNMT →	+1.014	+0.416	<.001	.004	3	3
CCRCC	PACS2_S453 →	-0.374	-0.187	.001	.003	3	3
COAD	TNS1 →	+0.518	+0.252	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,926 associations by consensus.

CYP19A1 vs MAP1B — COAD

Explore this scatter interactively →