CYP17A1

Across TCGA patient cohorts, CYP17A1 protein abundance is significantly associated with the RNA expression of many other genes, with 584 significant associations in total. OV shows the largest number of these associations.

The most reproducible CYP17A1-associated genes across cancer lineages are MYH9, TCL1A, and RBBP8. Each is linked with CYP17A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP17A1-to-partner and partner-to-CYP17A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP17A1 versus MYH9 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP17A1→partner) and Y-score (partner→CYP17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MYH9 →	-1.661	-0.961	.006	.006	3	1
OV	TCL1A →	-0.971	-0.737	.003	.002	3	1
OV	RBBP8 →	+0.979	+1.259	.002	.001	3	1
OV	PIM2 →	-1.404	-1.147	<.001	.005	3	1
OV	CD40LG →	-0.836	-1.409	.004	.008	3	1
OV	CRISPLD2 →	-2.017	-1.439	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 584 associations by consensus.

CYP17A1 vs MYH9 — OV

Explore this scatter interactively →