CYP11B1

Across TCGA patient cohorts, CYP11B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,294 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYP11B1-associated GO terms across cancer lineages are T cell receptor signaling pathway, Cell adhesion mediated by integrin, and Lymphocyte apoptotic process. Each is linked with CYP11B1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CYP11B1-to-partner and partner-to-CYP11B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell receptor signaling pathway grouped by CYP11B1-low versus CYP11B1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP11B1→partner) and Y-score (partner→CYP11B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	T cell receptor signaling pathway →	+0.053	+0.046	<.001	<.001	3	12
STAD	Cell adhesion mediated by integrin →	+0.053	+0.044	<.001	<.001	3	12
STAD	Lymphocyte apoptotic process →	+0.054	+0.053	<.001	<.001	3	11
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.052	+0.043	<.001	<.001	3	11
STAD	Regulation of adaptive immune response →	+0.043	+0.046	<.001	<.001	3	11
STAD	Response to type II interferon →	+0.048	+0.043	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,294 associations by consensus.

T cell receptor signaling pathway by CYP11B1 expression — STAD

Explore this box plot interactively →