CYP11A1

Across TCGA cell cohorts, CYP11A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,613 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYP11A1-associated GO terms across cancer lineages are Biological process involved in symbiotic interaction, Maintenance of protein location, and Viral life cycle. Each is linked with CYP11A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYP11A1-to-partner and partner-to-CYP11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biological process involved in symbiotic interaction grouped by CYP11A1-low versus CYP11A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP11A1→partner) and Y-score (partner→CYP11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Biological process involved in symbiotic interaction →	+0.108	+0.720	<.001	.003	3	8
SOFT_TISSUE	Maintenance of protein location →	+0.140	+0.863	<.001	<.001	3	8
BONE	Viral life cycle →	+0.091	+0.581	<.001	.003	2	9
SOFT_TISSUE	Maintenance of protein location in cell →	+0.155	+0.931	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of post-translational protein modification →	+0.029	+0.204	.001	.008	3	8
BLOOD_Lymphoma	Spermatid development →	-0.030	-0.158	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,613 associations by consensus.

Biological process involved in symbiotic interaction by CYP11A1 expression — BONE

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