Across TCGA cell cohorts, CYLC1 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CYLC1-associated genes across cancer lineages are MMP27, FOLR3, and DEFB4B. Each is linked with CYLC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYLC1-to-partner and partner-to-CYLC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYLC1→partner) and Y-score (partner→CYLC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	2
LUNG_NSCLC_LUAD	FOLR3 →	+0.794	+2.733	<.001	.005	3	2
SOFT_TISSUE	DEFB4B →	+0.090	+4.977	<.001	.002	3	1
SOFT_TISSUE	SLC22A25 →	+0.022	+4.882	<.001	.001	3	1
SOFT_TISSUE	OR52E5 →	+0.025	+4.977	<.001	.002	3	1
SOFT_TISSUE	CFHR2 →	+0.087	+4.882	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration

CYLC1 survival (RNA) · tumor vs normal (RNA) · all CYLC1 data types