Across TCGA patient cohorts, CYHR1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYHR1-associated genes across cancer lineages are YAP, C-Raf, and Notch1. Each is linked with CYHR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYHR1-to-partner and partner-to-CYHR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYHR1→partner) and Y-score (partner→CYHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YAP →	+0.187	+3.009	.023	.019	3	1
UCEC	C-Raf →	+0.249	+3.169	.001	.020	2	1
UCEC	Notch1 →	+0.329	+3.169	<.001	.020	1	1
UCEC	Annexin-1 →	+0.884	+3.169	.002	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

CYHR1 survival (RNA) · tumor vs normal (RNA) · all CYHR1 data types